STATE OF RENIN-ALDOSTERONE SYSTEM IN PATIENTS WITH ACROMEGALIA

Verbovoy Andrey Feliksovich, Doctor of medical sciences, professor, head of sub-department of endocrinology, Samara State Medical University(Samara, 89 Chapaevskaya str.), diacenter@sama.ru
Kosareva Ol'ga Vladislavovna, Candidate of medical sciences, associate professor, sub-department of endocrinology, Samara State Medical University (Samara, 89 Chapaevskaya str.), kosareva1974@mail.ru
Sharonova Lyudmila Aleksandrovna, Candidate of medical sciences, assistant, sub-department of endocrinology, Samara State Medical University(Samara, 89 Chapaevskaya str.), lyuda163@mail.ru

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The article presents the results of examination of aldosterone, renin, insulin, insulin resistance in patients with acromegaly. Aldosterone levels is increased in all patients with acromegaly. Increased renin activity is found only in patients with hypertension in the active stage of disease. The authors have found a positive correlation of aldosterone and renin to the HOMA-IR, insulin, IGF-1.

acromegaly, aldosterone, renin, insulin.

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